The annotation score provides a heuristic measure of the annotation nội dung of a chrissiemanby.comKB entry or proteome. This score cannot be used as a measure of the accuracy of the annotation as we cannot define the "correct annotation" for any given protein.More...

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-Protein inferred from homologyi

This indicates the type of evidence that supports the existence of the protein. Note that the "protein existence" evidence does not give information on the accuracy or correctness of the sequence(s) displayed.More...


Select a section on the left khổng lồ see nội dung.

This section provides any useful information about the protein, mostly biological knowledge.More...

Functioni

Caution
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Information which has been imported from another database using automatic procedures.

More...

Automatic assertion inferred from database entriesi

This subsection of the Function section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.More...

Catalytic activityi
2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2OUniRule annotation

Information which has been generated by the chrissiemanby.comKB automatic annotation system, without manual validation.

More...

Automatic assertion according lớn rulesi
EC:4.2.1.9UniRule annotation

Automatic assertion according to rulesi


Source: Rhea. Show »« Hide
2,3-dihydroxy-3-methylbutanoate
*
">zoom
=
3-methyl-2-oxobutanoate
*
">zoom
+
H2O
*

This subsection of the "Function" section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinch, iron, & copper in various oxidation states. Others, such as most vitamins, are organic.More...

Cofactori
<4Fe-4S> clusterUniRule annotation

Automatic assertion according to rulesi

Note: Binds 1 <4Fe-4S> cluster.UniRule annotation

Automatic assertion according khổng lồ rulesi


This subsection of the "Function" section describes the metabolic pathway(s) associated with a protein.More...

Pathwayi: L-isoleucine biosynthesisThis protein is involved in step 3 of the subpathway that synthesizes L-isoleucine from 2-oxobutanoate.UniRule annotation

Automatic assertion according to rulesi

Proteins known to lớn be involved in the 4 steps of the subpathway in this organism are: This subpathway is part of the pathway L-isoleucine biosynthesis, which is itself part of Amino-acid biosynthesis.View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-isoleucine from 2-oxobutanoate, the pathway L-isoleucine biosynthesis & in Amino-acid biosynthesis.
Pathwayi: L-valine biosynthesisThis protein is involved in step 3 of the subpathway that synthesizes L-valine from pyruvate.UniRule annotation

Automatic assertion according khổng lồ rulesi

Proteins known to be involved in the 4 steps of the subpathway in this organism are: This subpathway is part of the pathway L-valine biosynthesis, which is itself part of Amino-acid biosynthesis.View all proteins of this organism that are known to lớn be involved in the subpathway that synthesizes L-valine from pyruvate, the pathway L-valine biosynthesis & in Amino-acid biosynthesis.
SitesFeature keyPosition(s)DescriptionActionsGraphical viewLength

This subsection of the Function section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the "Description" field.More...

Metal bindingi
123Iron-sulfur (4Fe-4S)UniRule annotation

Automatic assertion according to rulesi

1
Metal bindingi195Iron-sulfur (4Fe-4S)UniRule annotation

Automatic assertion according lớn rulesi

1

The Gene Ontology (GO) project provides a phối of hierarchical controlled vocabulary split inlớn 3 categories:More...

GO - Molecular functioni
Complete GO annotation on QuickGO ...
GO - Biological processi
Complete GO annotation on QuickGO ...

chrissiemanby.comKB Keywords constitute a controlled vocabulary with a hierarchical structure. Keywords summarise the content of a chrissiemanby.comKB entry và facilitate the tìm kiếm for proteins of interest.More...

Keywordsi
Molecular functionLyaseUniRule annotation

Automatic assertion according khổng lồ rulesi

Imported

Automatic assertion inferred from database entriesi

ARBA annotation

Automatic assertion according to lớn rulesi

Biological processAmino-acid biosynthesis, Branched-chain amino acid biosynthesisUniRule annotation

Automatic assertion according khổng lồ rulesi

ARBA annotation

Automatic assertion according to rulesi

Ligand4Fe-4SUniRule annotation

Automatic assertion according to rulesi

ARBA annotation

Automatic assertion according khổng lồ rulesi

, Iron, Iron-sulfur, Metal-binding
Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi
UPA00047;UER00057UPA00049;UER00061

This section provides information about the protein và ren name(s) and synonym(s) and about the organism that is the source of the protein sequence.More...

Names và Taxonomyi

This subsection of the Names và taxonomy section provides an exhaustive menu of all names of the protein, from commonly used to lớn obsolete, to allow unambiguous identification of a protein.More...

Protein namesi

Recommended name:
Dihydroxy-acid dehydrataseUniRule annotation

Automatic assertion according lớn rulesi

(EC:4.2.1.9UniRule annotation

Automatic assertion according lớn rulesi

)
Short name:
DADUniRule annotation

Automatic assertion according lớn rulesi


This subsection of the Names và taxonomy section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: "Name", "Synonyms", "Ordered locus names" và "ORF names".More...

Gene namesi

Name:ilvImported

Automatic assertion inferred from database entriesi


Synonyms:ilvDUniRule annotation

Automatic assertion according lớn rulesi


ORF Names:AFERRI_370019Imported

Automatic assertion inferred from database entriesi


This subsection of the Names & taxonomy section provides information on the name(s) of the organism that is the source of the protein sequence.More...

Organismi
Acidithiobacillus ferrivoransImported

Automatic assertion inferred from database entriesi

This subsection of the Names & taxonomy section shows the unique identifier assigned by the NCBI lớn the source organism of the protein. This is known as the "taxonomic identifier" or "taxid".More...

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Taxonomic identifieri
160808

This subsection of the Names và taxonomy section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.More...

Taxonomic lineagei
cellular organisms › Bacteria › Proteobacteria › Acidithiobacillia › Acidithiobacillales › Acidithiobacillaceae › Acidithiobacillus

This subsection of the Names và taxonomy section is present for entries that are part of a proteome, i.e. of a set of proteins thought to be expressed by organisms whose genomes have sầu been completely sequenced.More...

Proteomesi

This section provides information on sequence similarities with other proteins và the domain(s) present in a protein.More...

Family và Domainsi

Coiled coilFeature keyPosition(s)DescriptionActionsGraphical viewLength

This subsection of the "Family và domains" section denotes the positions of regions of coiled coil within the protein.More...

Coiled coili
226 – 246Sequence analysis

Automatic assertion according to sequence analysisi

Add BLAST
21

This subsection of the "Family & domains" section provides information about the sequence similarity with other proteins.More...

Sequence similaritiesi
Belongs to lớn the IlvD/Edd family.UniRule annotation

Automatic assertion according lớn rulesi

ARBA annotation

Automatic assertion according lớn rulesi


Keywords - DomainiCoiled coilSequence analysis

Automatic assertion according to lớn sequence analysisi

Family và domain name databases

Gene3 chiều Structural and Functional Annotation of Protein Families

More...Gene3Di
3.50.30.80, 1 hit

HAMAPhường database of protein families

More...HAMAPi
MF_00012, IlvD, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi
View protein in InterProIPR042096, Dihydro-acid_dehy_CIPR004404, DihydroxyA_deHydtaseIPR000581, DiOHA_6PGluconate_deHydtaseIPR020558, DiOHA_6PGluconate_deHydtase_CSIPR037237, IlvD/EDD_N

Pfam protein tên miền database

More...Pfami
View protein in PfamPF00920, ILVD_EDD, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi
SSF143975, SSF143975, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi
TIGR00110, ilvD, 1 hit

PROSITE; a protein tên miền & family database

More...PROSITEi
View protein in PROSITEPS00886, ILVD_EDD_1, 1 hitPS00887, ILVD_EDD_2, 1 hit

This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent khổng lồ the sequence(s), including length and molecular weight. The information is filed in different subsections. The current subsections và their nội dung are listed below:More...

Sequencei

This subsection of the Sequence section indicates if the canonical sequence displayed by mặc định in the entry is complete or not.More...

Sequence statusi: Complete.
A0A060UN89-1 FASTAAdd khổng lồ basketAdded to lớn basket
« Hide

10 20 30 40 50MSDNRRSKTV TQGVQRSPNR ALLRAVGFGD QDFDKPIVGV ANAHSSITPC 60 70 80 90 100NIGIGALATR AEAALKAAGA MPQTFGTITI SDGISMGTAG MKYSLVSREV 110 120 130 140 150IADSIETVCQ GQSMDGVLAL GGCDKNMPGA MIAIARMNIP. AIFVYGGTIK 160 170 180 190 200PGHYRGQDLT IMSAFEAVGQ HTVHKIDDEE LLEIERRACPhường. GAGSCGGMYT 210 220 230 240 250ANTMSSIFEA MGMSLPYSST MAAEDAEKAE SAAQSAEVLV SAIQKQILPR 260 270 280 290 300QILTRQAFEN AIAVAMAVGG STNAVLHLLA IAHAAQVPLT LDDFEAMRGR 310 320 330 340 350VPVLCDLKPS GRFVATDLHR AGGIPQVMKI LLAHGVLHGD ALTISGQTLA 360 370 380 390 400EVLQDVPSEA RTDQEVIRPW NHPIYAQGHL AILKGNLAPE GAVAKITGFI 410 420 430 440 450THKITGPARV FESEESCMKA ILAQKIKPGD VVVIRYEGPK GGPGMREMLS 460 470 480 490 500PTSAIIGEGL GDSVGLITDG RFSGATYGMV VGHVAPEAAV GGTIALVIEG 510 520 530 540 550DSVTIDPEQR LLQLNVSDEE IERRRAVWQA PAPRHTRGVL AKYAKLVSSA SKGAVTD
Show »
Length:557
Mass (Da):58,557
Last modified:September 3, năm trước - v1
The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.

It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.

However chrissiemanby.comKB may contain entries with identical sequences in case of multiple genes (paralogs).

The checksum is computed as the sequence 64-bit Cyclic Redundancy Cheông xã value (CRC64) using the generator polynomial: x64 + x4 + x3 + x + 1. The algorithm is described in the ISO 3309 standard.

Press W.H., Flannery B.Phường., Teukolsky S.A. & Vetterling W.T. Cyclic redundancy và other checksums Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993))

Checksum:iB4E6F6A0E442B3AD
BLASTProtParamProtScaleCompute pI/MWPeptideMassPeptideCutterGO
Sequence databases
Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CCCS020000031 Genomic DNA Translation: CDQ09915.1

NCBI Reference Sequences

This section provides liên kết to lớn proteins that are similar to lớn the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% & 50%) based on their membership in chrissiemanby.com Reference Clusters (UniRef).More...

Similar proteinsi


ProteinSimilar proteinsSpeciesScoreLengthSource
A0A060UN89Dihydroxy-acid dehydratase
ACIF2
557UniRef90_B7JB12
Dihydroxy-acid dehydratase
ACIFR
557
Dihydroxy-acid dehydratase (Fragment)
Acidithiobacillus ferrivorans
490
Dihydroxy-acid dehydratase
Acidithiobacillus sp. "AMD consortium"
557
Dihydroxy-acid dehydratase
Acidithiobacillus ferrivorans SS3
557
+12

Full view
ProteinSimilar proteinsSpeciesScoreLengthSource
A0A060UN89Dihydroxy-acid dehydratase
GLOVI
560UniRef50_Q7NGK1
Dihydroxy-acid dehydratase
BURTA
557
Dihydroxy-acid dehydratase
METPP
560
Dihydroxy-acid dehydratase
LEPIN
560
Dihydroxy-acid dehydratase
LEPIC
560
+2408

Full view

This section is used to lớn point to information related lớn entries & found in data collections other than chrissiemanby.comKB.More...

Cross-referencesi

Sequence databases
Select the link destinations:EMBLiGenBankiDDBJi
Links Updated

Database of comparative sầu protein structure models

More...ModBasei
Search...

SWISS-MODEL Interactive sầu Workspace

More...SWISS-MODEL-Workspacei
Submit a new modelling project...
Enzyme và pathway databases
UniPathwayiUPA00047;UER00057UPA00049;UER00061
Family & tên miền databases
Gene3Di3.50.30.80, 1 hit
HAMAPiMF_00012, IlvD, 1 hit
InterProiView protein in InterProIPR042096, Dihydro-acid_dehy_CIPR004404, DihydroxyA_deHydtaseIPR000581, DiOHA_6PGluconate_deHydtaseIPR020558, DiOHA_6PGluconate_deHydtase_CSIPR037237, IlvD/EDD_N
PfamiView protein in PfamPF00920, ILVD_EDD, 1 hit
SUPFAMiSSF143975, SSF143975, 1 hit
TIGRFAMsiTIGR00110, ilvD, 1 hit
PROSITEiView protein in PROSITEPS00886, ILVD_EDD_1, 1 hitPS00887, ILVD_EDD_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti
Search...

MobiDB: a database of protein disorder & mobility annotations

More...MobiDBi
Search...

This section provides general information on the entry.More...

Entry informationi

This subsection of the "Entry information" section provides a mnemonic identifier for a chrissiemanby.comKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration inkhổng lồ chrissiemanby.comKB/Swiss-Prot.More...

Entry namei
A0A060UN89_9PROT

This subsection of the "Entry information" section provides one or more accession number(s). These are stable identifiers và should be used to cite chrissiemanby.comKB entries. Upon integration inlớn chrissiemanby.comKB, each entry is assigned a chất lượng accession number, which is called "Primary (citable) accession number".More...

Accessioni
A0A060UN89Primary (citable) accession number: A0A060UN89

This subsection of the "Entry information" section shows the date of integration of the entry inkhổng lồ chrissiemanby.comKB, the date of the last sequence update & the date of the last annotation modification ("Last modified"). The version number for both the entry & the canonical sequence are also displayed.More...

Entry historyi
Integrated into lớn chrissiemanby.comKB/TrEMBL: September 3, 2014
Last sequence update: September 3, 2014
Last modified: February 10, 2021
This is version 39 of the entry and version 1 of the sequence. See complete history.

This subsection of the "Entry information" section indicates whether the entry has been manually annotated and reviewed by chrissiemanby.comKB curators or not, in other words, if the entry belongs to lớn the Swiss-Prot section of chrissiemanby.comKB (reviewed) or to the computer-annotated TrEMBL section (unreviewed).More...

Entry statusi
Unreviewed (chrissiemanby.comKB/TrEMBL)

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